V for Vitrification # A to Z Challenge

DISCLAIMER

Vitrification in IVF can allow freezing of spare embryos with better post-thaw survival rates and higher pregnancy and live birth rates from frozen embryo transfer cycles. In simple terms Vitrification means freezing the embryos and also oocytes /eggs, for later or future use.

15245749025061647027547.jpg

vitrification is a solid glass-like cell, free of ice crystals.Vitrification can efficiently preserve spare eggs and embryos, so they can be used later on to achieve a pregnancy after thawing. Survival rates after vitrification and subsequent pregnancy rates are much better than they were with conventional slow freezing.

Vitrification is dependent on the placement of the oocyte/embryo in a very small volume of vitrification medium which is then cooled at an extreme rate, so that the embryos are flash frozen and preserved intact,content source, here.

--------------------------------------------------------------------------------------------------------------------------------------


PS:I am not a doctor, these are just my findings, my experiences and my infertility warrior friends experiences,which are a part of my life. I am half doctor myself because we go though so much,sometimes I feel I know my diagnosis better than my RE(Reproductive Endocrinologist). Hope these posts make some sense for people who are not a part of this journey.This post is a part of #AtoZchallenge2018.

E for Expectations # A to Z Challenge

DISCLAIMER

We infertility warriors have loads of expectations with the treatment, obviously we have all the right to have expectations isn’t it,because with all the promises , guarantees and the money we invest, yes I call it investment.The infertility treatments are emotionally, physically and financially draining, but we go thought it because we genuinely  expect what is promised, that too the most wanted .When we start our infertility journey we think finally we will be getting answers, for why the hell we are not able to conceive.We will get few answers few even the doctor will not be able to tell, even the modern science does not have answers for certain things.

images (4)

When we started the treatment, I can specifically talk about IVF journey cause I am going through it right now, there different types of protocols and treatment depending upon each person and their issues regarding infertility.

So coming back to the topic when I told that I can have my own baby with IVF procedure I was on cloud nine, I was expecting this from my doctor, because I dint want any other procedure, which does not have that much success rate compared to IVF, IVF too has just 40 to 70 percent depending on each person, but better success rate then other procedures, so obviously we will have the exceptions, but these exception can give u a big jolt when things don’t turn out the way you want it to be or the way it was promised,

My friend who had IVF procedure almost same time as me, she got pregnant in  first transfer (FET)itself but had to miscarry because the fetus was not developing and no heartbeat,one more friend her embryos dint survive at until day 5 , she has to to 2nd round of IVF go through all the drill all over again, many more sad stories about people who i know who go through infertility, and about me my embryos are frozen, my endometrial lining is not growing according to my RE’s satisfaction, so from January my embryo transfer is being  postponed, she has some plan this month hopefully it will work for me,  all my expectations are gone in the drain, but we are normal humans, we cant stop having exceptions again an again and be disappointed, this is infertility life.

Starting All Over Again – FET

DISCLAIMER

IMG-20180208-WA0022

In my last post I had written that I might get my period by 5th or 6th of Feb, but AF arrived very soon, on Friday 2nd Feb I was spotting and on 3rd morning I knew that my period is in the way, but I was spotting until noon, so I was darn worried  about when should I go, on day 2 or wait until Monday day 3, because RE  wanted me to come on day 2 after getting my period, and my day 2 would have been Sunday the 4th sigh,my life around is IVF is always confused.

 

 

I rang my clinic to tell about my confusion they told me to come on Monday day 3 no problem, so on Monday 5th Feb day 3 of I went to meet RE. I hate those TVS/ultrasound scan specifically on the bleeding days, but cant help you know that.RE did the scan and told everything looks fine 5 mm lining is shedding, no cysts and all.

images (3)

So again my RE gave those same dose as last time  Progynova 2 mg (estrogen) tabs one in the morning and one in the night exactly after twelve hours for three days until day 6, and from day 7 two tabs in the morning and two in the night and same twelve hours apart .I am on EV progynova tabs from day 3, last time I was the same tab my period stopped on day 4 and day 4 it was almost only spotting, this time I had my bleeding until day 6, so I am darn worried that about my lining, will it grow this time or what, this journey as made me very negative seriously, I was never ever  a negative person but life situations make me like this.

images

I have an appointment on day 12 ,14th Feb what a day for me, what say. I am hoping my lining will grow by then, please pray for me and any tips for the lining to grow thank in advance, will update soon.

IVF – Part 4

DISCLAIMER

Happy new year to all my readers, have a great year ahead and hope all dreams come true and hold out babies soon. All the TTC ladies are in my prayers.I still can’t believe its 2018. Last Jan when I was in the middle of the infertility treatment, I was still in those beginning phase of the treatment and was so sure will conceive in one of those clomid or one of the IUI’s, but the universe had some other plans I guess. As I type this, still there is no baby in my belly. I could have been PUPO(Pregnant Until Proven) by yesterday but I asked my RE for day five transfer.

textgram_1514810358

Ok coming back to the part 4 of out IVF, on 29th  Dec 2017 on the auspicious day of Vaikunta Ekadhasi according to our Hindu calendar, my egg pick up/retrieval (ER) was done by 1.30 pm, according to my trigger shot timings of 35 to 36 hours.I was praying that I should get at least 12 to 15 eggs, but we got only 10.In the morning before ER BH had to give fresh SA, but he had to give it soon , as he had some important meeting , so there was so much confusion but finally the embryologist agreed to give it sooner and BH gave the fresh sample left, even though there was frozen back up, that morning confusions was very taxing.

After the ER , when I woke up, RE came up to me and told that they got 10 eggs, lets see how the fertilization is, we will know about it tomorrow and went away before I could ask any questions.I was very angry about myself that I got only 10, by then my friend F came to meet me,  about whom I have mentioned   here and here. My friend told why are you even feeling bad when others don’t even get a egg or more less than yours, I was like I am worried about me I din’t want to compare  myself with anyone at that point.Anyways I felt better speaking to her.

textgram_1514810974

When I was declared fine by the duty doctor to go home,RE had  prescribed some tabs until I meet her on Monday day 3, seeing those tabs , my friend F told you might have fresh transfer, I was like it cant be, but those tabs were for readying me for the fresh transfer. I was confused and shocked cause I had prepared myself mentally for FET. I have written about it here so many times.I am on vaginal progesterone and one more tab I don’t know the name the other tablet for preparing for ET, those tabs are making me feel confused, heart burn,nauseous and very tired.

IMG_8533

I left the clinic praying all of our  eggs to be fertilized and not to think about the ET (Embryo Tranfer). Until the next day I was so darn nervous, until I got to know about our fertiliation. The report was 9 eggs were mature and 7 had fertilized, that was a ok news o me, I was ok fine. Then prayed that they all grow fine, praying was the only choice I had, that’s what I did on the last weekend of 2017.

Monday JAN 1 st 2018, I went to the clinic, the junior doc did the scan, she told my lining is good and after ER there was some fluid  in the utreus, that fluid was also not there everything was looking good , so they wanted me to do day three transfer.I was not able to react, I asked can we do day 5 transfer, the blastocyst transfer,they were like we will check with RE and then decide.

images (7)

 

I met the RE she was busy with ER with other patients, she said.She told that success rate does not vary much, most of my patients have had success with day 3 transfer, decide what you want and called the embryologist. The embryologist showed me the report, all 7 were going good on day 3,only one was slight behind but that also was good grade, they told it might catch up.

fa621e14fa054fe9a1843c885f09c091

This was the first time in my life that I took decision without consulting BH / mom/ mil or anyone,and the decision was made within a minute, I just told, that mentally blastocyst  transfer would be fine for me.Now tomorrow I will know how many have made it to blasts.RE suggested that if I want day 5 transfer then freeze two day 3 embryo which are actually really good,remaining 5 we can let it grow, in case we lose all during the day 5 we have two day 3 back up, so fingers crossed that all five grow on day 5, and I can get done with ET tomorrow, my friend  F told that even her  few d grade embryo grew until day 5, mine was grade b embies so it should grow fine she told, I was nervous after taking the decision she told just go with the flow it will work out. Please pray that my embryos grow and I can have ET tomorrow.

LIFE & TIMES

DISCLAIMER 

I have been a bit busy with loads of things in life. Sometimes life give us such a twist or a jolt I must say.I wanted to write so much, I  wanted to update here as much as possible, but some times life just fully pulls you into its in unpredictable ways .I am not working as of now, I am glad I am and not working or looking after my dads business at this point of time. Actually that’s what I was doing before, but those things are changing for time being. My dads not well, and will be going for surgery on Monday, he neglected his health now its like he has to be operated to be fine.It is not a major or minor surgery, its something in between,so my dads doctor has told that he will be fine and not to worry so that’s a relief as of now.

a1fbee3d5dd2d8643d0d94b697fe38d5

So yes, its a surgery for him and also I guess I will be starting my injection/simulations and scans and what not I don’t know at the same time I guess. I should get my period by Monday, sometimes my periods are irregular so I don’t know when AF will start and when I will start IVF. I have written and said this hundred times,  and I will say it again and again until I am done , I am excited and nervous at the same time for the IVF sigh.


UPDATES

Last week we had gone to the clinic to show some of my pending reports and BH had to give semen for freezing. Freezing is just a back up, he has do do it again😁 during egg retrieval, for fresh sample, sigh. When I asked them why twice🤔, they told sometimes husbands wont be able to give sample on egg retrieval day, they are nervous or whatever, that’s why back up they told.

cb1760afedd627c01e18fca0b05a04c3

My reports sigh, its a never ending saga. In the hospital I did Hystro-lap  did not give TB PCR report, the explanation for that is if APF culture  is fine/ negative means everything  is fine and that’s what even RE told last time but still she wanted the report, anyways after speaking to hundred people in the hospital they told the same story that that is APF report is fine means they don’t do TB PCR test, and that they would reimburse the money which I paid for the test.

I went to the hospital  last Monday to get my money back, they told it will take two to three days, but  its more then two weeks I have still not got the money. I called this Wednesday,because I din’t get any call from the hospital, they told me to come on Friday but I am a bit busy today will be going tomorrow, hopefully without any drama they will reimburse my money.


As I said that I have been busy with so many things happening in life, yesterday I had a very nice break. I had to go somewhere, but it got cancelled at the last minute, so I went to parlor got a nice facial done, it was  so very relaxing. I came back home and no one was there at home, so saw a Hindi movie after such a long time, it was so so so… good and relaxing and I enjoyed the movie, without any interruption, then I slept nicely , got up made nice my favorite black coffee just people watched from balcony/patio it was a great day.

images (2)

My BFF forced me to tell Vishnu Sahasranaman , she felt it will do good for my IVF cycle spiritually. My BFF is in London from 4 years, but the distance has made no difference in our friendship, she keeps giving me spiritual advice’s and I am glad to have her as my friend  and we connect you see. I am already doing lot spiritually, prayers and poojas, but she told just recite Vishnu Sahasranamam, so I started it from last Monday, I feel very nice and calm, Thank you R.


Hopefully AF will start soon and I can start with IVF, this waiting game is very frustrating.It’s either waiting because of the blood, biopsy or whatever test reports, then the doctors or clinic mistakes, doctors timings and my own body which I don’t want to talk negative about. It’s CD 33 and I am still waiting for AF. Hopefully I will start soon :).

 

 

Never Ending ….

DISCLAIMER

Until I start IVF it is never ending reports and meeting the doctors. I knew all this but it feels never ending . I met RE on Monday, seeing my  AMH and BH’s semen analysis she told we’ll do two IUI’s if that does not work we can start IVF, she told this even before seeing my other reports. I told her that both my tubes are blocked , she was like “oh I did not see that”,So its IVF for you she told, I knew that thank you.

d23ef577a5fe999ac025f8fbba37fb6b--travel-photos-thoughts-and-quotes

Then she checked my other reports and told everything is fine, but I cant find TB PCR report and discharge summary after Hystro-laparoscopy , sigh. I had to go back to the hospital where my gynecologist did hystro-lap and get both those reports, it’s never ending I must say. When I went to the hospital to take my report first they told I will get the report in  ten minutes then , later they told it will come by evening. then next day never ending did I say.

Next day I called in the morning, they told they will call back in 10 minutes but I never got call until 3 pm, I called them and scolded them. At that time they are telling that if AFP culture, smear , tissue  whatever all the reports are negative/fine means PCR also will be negative so  they don’t test that and I can take back that money, I was relieved but also  irritated with all this, and felt so many hurdles before I start IVF.

3379902-future-in-gods-hands

Ok coming back to my meeting with RE, she then explained that I will be starting IVF from second day of my period. They will be doing IVF- ICSI , even though BH’s SA is good. When I asked why? they told the success rate is more in ICSI. Then she told that since my AMH is good I might have chances of OHSS, I was shocked, but was just listening, she told there are Chances of OHSS but I can’t tell it will happen , don’t worry much we will take care of you that’s what she told I think. So maybe it wont be a fresh transfer, we will do FET cycle , but fresh transfer or FET will be know depending upon how my health will be at that time. Then I asked the doctor for IVF many people start with Birth Control Pills(BCP) why she is starting for me from just day 2  , she told that in other clinics they take control of your cycle when there are too many patients, but here we concentrate on less people , so we start with second day of your periods, that’s it.

Then met the finance person, got the details, she explained well . She split the amount for what  is for what and all.The total cost of IVF , plus some MACS test for selecting best sperm for ICSI,  cost for freezing the  embryo for 4 , if there are more than four , again some more thousands of  rupees  sigh, then extra more  money if it is FET cycle . The injections can be taken by the nurse in the clinic she told, if my home is near, so mostly those injection days I  will be going to clinic daily I think so, even though the clinic is just 7 to 8 KM, but in this Bangalore traffic it will take 30 to 45 mins in non peak traffic time, so mostly the timing will be between 11 am to 12 pm noon.

cc2a07ba68f649940f731ab5ca122e5d--quotes-marriage-marriage-life

Then met the in house counselor who spoke very nicely, I felt good. She told me eat good food, not to eat out, walk as much as possible, yoga , pranayama , not to fall sick and in general spoke very nicely made me feel better, she also told I could speak to her if I want to, also there was a infertility talk next day , she told I could come if I want too. I also told about my blog and a India Infertility group me and a friend are trying to start so we can make others feel we are not alone. It was good.

e78f8c_737c9b724f014827bff3ce85cb0c9a48-mv2

Tomorrow again I will be meeting  RE again to give the final reports and BH will be giving semen for freezing, he can give fresh semen during egg retrival too, this just for a back up and we are  paying for semen freezing obviously .This  has become a never ending post, hopefully my meeting with RE go fine and I should go next on day 2 of my period for starting IVF.I need your prayers.